摘要
[目的]观察补阳还五汤加减对气虚质脑梗塞恢复期二级预防的疗效及其安全性。[方法]将107例气虚质脑梗塞恢复期患者按先后顺序随机分为观察组54例和对照组53例。两组在常规治疗的基础上,观察组予补阳还五汤加减辩证治疗6个月,同时给予口服阿司匹林;对照组给予口服阿司匹林;两组均随访6个月。比较两组患者缺血性脑卒中复发率、临床神经功能缺损、日常生活活动能力和中医症状评分的改善情况以及中药辩证施治的安全性。[结果]两组复发率差异无统计学意义(P>0.05);在改善临床神经功能缺损评分、日常生活活动能力评分、中医症状评分方面,观察组优于对照组(P<0.01);均未出现严重不良反应。[结论]补阳还五汤加减对气虚质脑梗塞恢复期二级预防有一定的疗效,是临床预防脑梗塞安全有效的方法之一。
[Objective] To observe the therapeutic effect and safety of Buyanghuanwutang for the secondary prevention of Qi-deficiency constitution type＇s ischemic cerebral apoplexy.[Methods] One hundred and seven cases of Qi-deficiency constitution type＇s ischemic cerebral apoplexy were randomly divided into an observation group and a control group according to the visiting sequence（54,53）.Both groups were treated on the base of the routine treatment,the observation group was treated with Buyanghuanwutang combined with oral administration of Aspirin for six months.The control group was treated with oral administration of Aspirinal one.Six-month follow-up was done in two groups.Then the recurrence rate of ischemic cerebral apoplexy,the improvement of neurologic impairment,activity of daily living and TCM symptomscores and the safety between two groups were compared.[Results] The recurrence rate was 10.20%（5/49） in observation group,and 16.89%（9/53） in control group.There was no significant difference between two groups.The observation group was superior to the control group in improving the scores of the nerrologic impairment,activity of daily living and TCM symptom.There was no severe adverse reaction in two groups except 2 cases of gastrointestinal reaction caused by oral administration of Aspirin incontrol group.[Conclusion] Buyanghuanwutang has a certain therapeutic effect for the secondary prevention of Qi-deficiency constitution type＇s ischemic cerebral apoplexy,and it is one of the safe and effective methods for preventing ischemic cerebral apoplexy in clinic.
出处
《浙江中医药大学学报》
CAS
2011年第6期836-838,共3页
Journal of Zhejiang Chinese Medical University
基金
河北省石家庄市科技局资助项目(NO:091461303)~~
