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乳腺癌手术后辅助内分泌治疗研究进展 被引量：13

Research progress in endocrine therapy for breast cancer
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摘要 内分泌治疗是激素受体阳性乳腺癌患者治疗的重要方式之一,但有部分激素受体阳性患者内分泌治疗无效。部分患者起初对内分泌治疗药物有效,随着疗程的延长疗效下降等。文中就内分泌治疗疗效的相关因素、芳香化酶抑制剂的应用、内分泌治疗耐药机制和内分泌治疗耐药逆转等研究的进展进行综述。 Endocrine therapy is one of the important methods for the treatment of receptor-positive breast cancer,though some receptor-positive patients fail to respond to it,and still others develop acquired endocrine resistance after an initial response.This article outlines the progress in the researches on endocrine therapy response-related factors,application of aromatase inhibitors,mechanisms of endocrine therapy resistance,and strategies to overcome endocrine resistance.
作者 顾军 于泽平
机构地区 南京军区南京总医院全军普通外科研究所
出处 《医学研究生学报》 CAS 北大核心 2012年第1期107-112,共6页 Journal of Medical Postgraduates
关键词 乳腺癌 内分泌治疗 雌激素受体 芳香化酶抑制剂 Breast cancer Endocrine therapy Estrogen receptor Aromatase inhibitor
分类号 R737.9 [医药卫生—肿瘤]
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参考文献45

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二级参考文献16

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医学研究生学报
2012年 第1期

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