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匹多莫德联合干扰素治疗小儿反复呼吸道感染疗效观察 被引量:33

The effects of Pidotimod combined with interferon on children's recurrent respiratory infection
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摘要 目的:观察匹多莫德联合干扰素治疗小儿反复呼吸道感染(RRTI)的临床疗效。方法:对照组采用常规治疗,治疗组在常规基础上给予干扰素雾化吸入和匹多莫德口服治疗,观察比较两组的总有效率、症状、体征及免疫学检查结果。结果:治疗组总有效率为86.0%,对照组总有效率为28.0%,两组比较P<0.05;治疗组发热、扁桃体肿大、肺内罗音的消退时间短于对照组;T细胞亚群CD4+较对照组升高,CD8+较对照组降低。结论:干扰素雾化吸入联合匹多莫德治疗RRTI有较好的临床疗效。 Objective:To observe the treatment effects of Pidotomod combined with interferon on children's recurrent respiratory infection.Methods:100 children with recurrent respiratory infection were divided into control group and treatment group randomly.The conventional therapy was used in control group;on a regular basis,the interferon atomization and oral Pidotimod were used in treatment group.The total effective rates of the two groups were observed.Results:The total efficiency was 88.6% in the treatment group and 28.0% in the control group,the difference was statistically significant,P0.05;And the subsided time of the fever,swollen tonsils,and roles in pulmonary in the treatment group were shorter than the control group;The level of CD4+ in treatment group was higher than the control group,the level of CD8+ in treatment group was lower than the control group.Conclusion:There is significant effects of Pidotomod on children's recurrent respiratory infection.
出处 《中国妇幼保健》 CAS 北大核心 2012年第5期696-697,共2页 Maternal and Child Health Care of China
基金 河北省唐山市科技局科技攻关项目〔06134618e〕
关键词 匹多莫德 干扰素 反复呼吸道感染 防治 Pidotomod Interferon Recurrent respiratory infection Prevention and cure
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