摘要
目的:了解和分析荆州市第一人民医院抗感染药致药品不良反应(ADR)发生的特点及规律,为临床合理用药提供依据。方法:对我院2010年临床各科室上报的279例抗感染药致ADR报告进行回顾分析。结果:279例抗感染药致ADR中,静脉滴注导致的ADR最多(262例,占93.55%);以头孢菌素类引起的ADR例数最多(101例,占36.20%),其次为氟喹诺酮类(68例,占24.37%);ADR累及的器官和(或)系统主要为皮肤及其附件(139例,占49.82%),其次为消化系统(77例,占27.60%);上报科室以外科最多(121例,占43.37%)。结论:不合理使用抗感染药是ADR产生的主要原因之一,应加强抗感染药的临床合理应用和ADR监测,保障公众用药安全。
OBJECTIVE： To probe into the characteristics and regularity of the adverse drug reactions （ADRs） induced by anti-infective drugs in Jingzhou First People＇ s Hospital so as to provide references for clinical rational drug use. METHODS： A retrospectively analysis was performed on 279 ADR cases induced by anti-infective drugs reported by clinical departments of our hospital during 2010. RESULTS ： Among the 279 ADR cases, 262 （ 93.55% ） were induced by intravenous drip infusion; 101 cases （36. 02% ） were induced by cephalosporins and 68 （24. 37% ） quinolones. Skin and its appendages were the predominant system and （organs） involved in the ADRs （139 cases, 49.82% ） followed by digestive system （77 cases, 27.60% ）. The ADR cases were mostly reported by surgical department（121 cases,43.37%）. CONCLUSION： Irrational use of anti-infective drugs was the main reason for adverse drug reaction, therefore, it is urgent to strengthen clinical rational use of anti-infective drugs and ADR monitoring to ensure patients＇ medication safety.
出处
《中国医院用药评价与分析》
2012年第1期71-73,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
抗感染药
药品不良反应
报告
分析
合理用药
Anti-infective drugs
Adverse drug reaction
Report
Analysis
Rational use of drugs
