摘要
目的:研究消癌平注射液中有机酸成分。方法:利用LC-MS分析消癌平注射液中有机酸类成分,并通过HPLC与对照品比对验证,用面积归一化法确定各成分的相对含量。结果:共鉴定了13个化合物,共占有机酸总量的50.33%,主要分析了新绿原酸、绿原酸和隐绿原酸的质谱裂解规律。结论:有机酸主要成分为新绿原酸(7.62%)、绿原酸(10.56%)、隐绿原酸(4.64%)、对香豆酸(4.22%)等。
Objective：To analyze the chemical constituents of organic acids in Xiaoaiping injection.Method：The constituents of organic acids were separated by LC-MS,and then the contents was identified by HPLC.Result：Thirteen compounds was identified,representing 50.33% of the total organic acids.And the fragmentation behaviors of three organic acids were investigated.Conclusion：The principle chemical constituents of organic acids in xiaoaiping injecton are neochlorogenic acid（7.62%）,chlorogenic acid（10.56%）,cryptochlorogenic acid（4.62%） and p-coumaric acid（4.22%）.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第4期88-90,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家"重大新药创新"科技重大专项项目(2011ZX09201-201-02)
