期刊文献+

急性心肌梗死患者血小板相关参数与血清同型半胱氨酸测定的临床意义 被引量:3

Clinical significance of Platelet-related parameters and serum homocysteine in the patients with acute myocardial infarction
原文传递
导出
摘要 目的:观察急性心肌梗死(AMI)患者的血小板相关参数、血清同型半胱氨酸的变化,探讨其检测在急性心肌梗死中的意义。方法:测定对照组与急性心肌梗死组治疗前后的血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)及血清同型半胱氨酸(Hcy)并对检验结果进行分析。结果:与对照组相比,AMI组治疗前MPV与PDW水平明显升高(P<0.01),Hcy水平升高(P<0.05),PLT水平明显降低(P<0.01),两组差别具有统计学意义,AMI组治疗后PLT水平上升,MPV、PDW、Hcy水平下降,与对照组相比差别无统计学意义。结论:监测血小板参数和Hcy的变化,有助于对急性心肌梗死的治疗和预后。 Objective:To analyse platelet related parameters and serum homocysteine levels and explore its significance in pa- tients with acute myocardial infarction (AMI). Methods: The determination results of platelet count (PLT), mean platelet vol- ume ( MPV), platelet distribution width (PDW) and serum homocysteine (Hcy) were compared and analysed between control group and acute myocardial infarction group before and after treatment. Results: Compared with the control group, the concentra- tion of MPV, PDW and Hcy of AMI group before treatment had a significantly higher level (P 〈 0.01 or P 〈 0.05 ), but the con- centration of PLT level reduced significantly (P 〈 0.01 ), and two groups had statistically significant differences. In AMI group after treatment, the PLT level raised, but levels of MPV, PDW and Hcy decreased, no statistical significance was found between AMI group and the control group. Conclusion: Monitoring the change of platelet parameters and Hcy can help the acute myocar- dial infarction treatment and prognosis.
出处 《中国卫生检验杂志》 北大核心 2012年第2期306-307,共2页 Chinese Journal of Health Laboratory Technology
关键词 急性心肌梗死 血小板 同型半胱氨酸 Acute myocardial infarction Platelet Homocysteine
  • 相关文献

参考文献5

  • 1Santiago E, Mora L, Bautista M, et al. Granulocyte colony - stimulating factor induce neutrophils to secrete macrophage colony - stimulating factor[J]. Cytokine, 2001,15(6) :299 -304.
  • 2田文洪.冠心病患者血小板参数的变化及临床意义[J].实用临床医学(江西),2004,5(3):43-43. 被引量:14
  • 3Wilken DE, Wilcken B. The pathogenesis of coronary artery disease : apossible role for methionine metabolism[ J]. J Clin Invest, 1976,57 (4) : 1079 - 1082.
  • 4朱立华,徐国宾,杨宏云.同型半胱氨酸与动脉粥样硬化[J].中华检验医学杂志,2001,24(2):121-123. 被引量:71
  • 5Cuba SC, Fink LM, Fonesca V. Hyperhomocysteinemia, an emerging and important risk factor for thromembolic and cardiovascular disease [J]. Am J Clin Pathol,1996,106(6) :709 -722.

二级参考文献5

共引文献83

同被引文献44

  • 1周俊,余意君,吴师伟.胱抑素C、IL-6在老年急性心肌梗死预后判定中的意义[J].中国老年学杂志,2014,34(12):3229-3230. 被引量:8
  • 2杨丽红,王明山,谢海啸,谢于鹏,王良兴.肺血栓栓塞症患者溶栓治疗时血小板参数的动态变化及临床意义[J].心肺血管病杂志,2004,23(3):139-140. 被引量:2
  • 3凌长春,宋后燕.组织型纤溶酶原激活剂潜在的中枢神经系统毒性作用[J].国际神经病学神经外科学杂志,2005,32(6):507-509. 被引量:1
  • 4蒋玲,任英,罗翠花.肺栓塞与血小板活化标志物[J].临床肺科杂志,2007,12(7):691-692. 被引量:13
  • 5陆再英,钟南山.内科学[M].7版.北京:人民卫生出版社.2011:79.
  • 6Varol E, Icli A, Uysal BA, et al. Platelet indices in patients with acute pulmonary embolism[J]. Scand J Clin Lab Invest, 2011,71 (2) : 163 -167.
  • 7Victoria A. Kopetz,Megan A.S. Penno,Peter Hoffmann,David P. Wilson,John F. Beltrame.Potential mechanisms of the acute coronary syndrome presentation in patients with the coronary slow flow phenomenon — Insight from a plasma proteomic approach[J]. International Journal of Cardiology . 2011 (1)
  • 8Effect of Early, Pre-Hospital Initiation of High Bolus Dose Tirofiban in Patients With ST-Segment Elevation Myocardial Infarction on Short- and Long-Term Clinical Outcome[J]. Journal of the American College of Cardiology . 2010 (22)
  • 9Shacham Y, Topilsky Y, Leshem-Rubinow E, et al. Comparison of left ventricular function following first ST-segment elevation myocardial infarction treated with primary pereutaneous coronary intervention in men versus women [J]. Am J Cardiol, 2014, 113 (12): 1 941-946.
  • 10Sedlak TL, Gao M, Lee M, et al. Outcomes and transfer patterns for first non-ST-elevation myocardial infarction (NSTEMI) : comparisons between community and tertiary care hospitals[J]. Can J Cardiol, 2014, 30 (12) : 1562- 569.

引证文献3

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部