摘要
目的探讨病灶清除术配合药物用于脊柱结核治疗的临床疗效。方法选择脊柱结核患者56例,经4～6周正规抗结核治疗后行手术治疗。手术方法选择病灶清除椎间植骨融合内固定术,术后行常规抗结核治疗12～18个月。结果①近期疗效:无患者出现脊髓及马尾神经损伤症状,无植骨块移位、脱落及金属内固定断裂,无大血管损伤。②远期疗效,患者治愈率为96.4%。植骨融合成功率为89.3%。43例患者体征消失,占76.8%,12例患者体征减轻,占21.4%,1例症状及体征无明显改善。29例存在脊柱畸形的患者中,基本矫正19例,部分矫正8例,无明显改善2例。③术前平均Cobb角为(17.2±6.8)°,术后平均(10.4±4.3)°,两者比较有统计学意义(P<0.05)。结论病灶清除术配合药物对脊柱结核治疗有良好的疗效,具有很高的应用价值。
Objective To study clinical curative effect of drug combining with operation of latibulum clearance for lesions spinal tuberculosis treatment. Methods Selected 56 cases of spinal tuberculosis patients. After 4 to 6 anti-tuberculosis treatment. Surgical method chosen drug combining with operation of latibulum clearance lesions bone graft fixation fusion, postoperative do regular antitubercular treatment 12 to 18 months. Results （1）Recent curative effect： no patients experienced the spinal cord and the nerve damage symptom, without cancellous bone piece of shift, fall off and metal fracture fixation, no big vascular injury. （2）The long-term outcome, patients cure rate was 96.4%. Cancellous bone fusion success rate of 89.3%. 43 patients signs disappeared, 76.8%, 12 patients reduce signs, accounting for 21.4%, and 1 case symptoms and signs have no obvious improvement. 29 cases of existence in patients with spinal deformity, basic correction （19 cases）, part correct 8 cases, no noticeable improvement in 2 cases. （3）The average Cobb Angle for preoperative（17.2 ±6.8）°, the average （10.4 ±4.3）°, There was a statistical difference（P 〈 0.05）. Conclusion Drug combining with operation of latibulum clearance lesions in spinal tuberculosis treatment has good curative effect and has the very high application value.
出处
《中国现代医生》
2012年第7期121-122,共2页
China Modern Doctor
关键词
脊柱结核
病灶清除术
药物
Spinal tuberculosis
Operation of latibulum clearance
Drug
