摘要
目的:观察补元汤加味对慢性阻塞性肺疾病BODE指数的影响。方法:将60例符合慢性阻塞性肺疾病稳定期诊断标准的患者,随机分为治疗组及对照组,每组各30例。治疗组服用中药汤剂:补元汤加味,每日1剂。对照组按需使用吸入型支气管舒张剂:可必特。两组观察时间均为6个月。每2个月对患者BODE指数各因素进行跟踪检测:体重指数、FEV1测定、呼吸困难分级、6min步行距离。动态观察两种治疗对各因素的影响程度及BODE指数水平的变化,并比较差异性。结果:治疗6个月后,治疗组与对照组相比较,FEV1%pred、6min步行距离(6MWT)、体重指数(BMI)、呼吸困难以及BODE指数改善明显(P<0.05)。治疗组在6个月的治疗过程中,随着疗程的增加,各项因素及BODE指数水平改善更加显著。结论:补元汤加味能有效改善COPD稳定期患者肺功能、运动耐力、营养状况及BODE指数,BODE指数是一项客观、系统的COPD稳定期疗效评价指标。
Objective ： To observe the effect of modified Buyuan Decoction on the BODE index in patients with chronic obstrutive pulmonary disease in stable stage. Methods：60 patients who met the Diagnostic Criteria for COPD in stable stage were randomly and equally divided into the treatment group （30 patients） and control group （30 patients） . The treatment group was given traditional Chinese medicine： modified Buyuan Decoction, one dose per day, while the control group was given Compound Ipratropium Bromide according to need. Six months are needed for clinical observation for the two groups. Then the factors of patient in every two months, such as body mass index （BMI）, FEV1, dyspnea grades, sixminute walking distance （6MWT） were tested. The changes in various factors and BODE index between two groups were compared. Results ： After 6 months＇ treatment, compared with those in the control group or before therapy, the levels of the various factors and BODE index in the treatment group were significantly improved（ P 〈0.05 ）, and the levels of the various factors and BODE index improved greatly with the increase of the treatment. Conclusion ： Clinical studies with modified Buyuan Decoction can improve lung function, exercise capacity, nutritional status and BODE index. BODE index is an objective and systematic evaluating indicator for curative effect in patients with chronic obstructive pulmonary disease in stable stage.
出处
《辽宁中医杂志》
CAS
2012年第3期482-485,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
江西省教育厅青年科学基金项目(GJJ09547)
关键词
补元汤
慢性阻塞性肺疾病
稳定期
BODE指数
Buyuan Decoction
chronic obstructive puhnonary disease
stable stage
BODE index
