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超声引导下局部注射甲氨蝶呤治疗异位妊娠的临床应用 被引量:4

The Clinical Application of Ultrasound-Guided Methotrexate Injection in Patients with Ectopic Pregnancy
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摘要 目的:探讨超声引导下局部注射甲氨蝶呤(MTX)治疗异位妊娠的疗效。方法:对30例异位妊娠患者在超声引导下行MTX病灶局部注射,术后给予米非司酮口服(25mg,2次/天,共3天)。治疗前及治疗后每周一次抽血查β-hCG直至其降至正常范围内。结果:30例患者中,29例(96.7%)通过治疗后β-hCG降至正常,1例(3.3%)治疗失败后行外科手术。结论:超声引导下MTX局部注射治疗异位妊娠技术操作简单,疗效肯定,对适应范围内的病人是值得考虑的治疗方法。 Objective: To evaluate the efficacy and safety of methotrexate(MTX) injection for ectopic pregnancy under ultrasound-guidance.Methods: 30 patients with ectopic pregnancy were treated with MTX injection under ultrasound-guidance followed by administration of mifepristone for 3 days(25mg,bid).Serum level of β-hCG was tested before treatment and then once a week after MTX injection.Results: 2-12weeks after MTX injection,β-hCG turned to be negative in 29 patients(96.7%).1 patient(3.3%) received operation because of the rupture lesion.Conclusion: Within considerable indication,MTX injection under ultrasound-guidance is effective and safe for patients with ectopic pregnancy.
出处 《现代生物医学进展》 CAS 2012年第3期476-478,452,共4页 Progress in Modern Biomedicine
关键词 超声引导 异位妊娠 甲氨蝶呤 局部注射 Ultrasound-guidance Ectopic pregnancy Methotrexate Local injection
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