摘要
目的探讨重组脑利钠肽对急性心梗患者介入术后疗效的临床研究。方法 60例急性心梗介入术后患者按随机数字表均分为两组,每组各30例。重组脑利钠肽组(研究组)于术后静脉应用重组脑利钠肽;硝酸甘油组(对照组)使用静脉持续滴注硝酸甘油。观察治疗前后生命体征、心功能分级、血清脑利钠肽、心梗指标和液体出入量。结果两组术后血浆BNP浓度、心肌酶谱、出入量均有明显差异。两组不良反应比较,差异有统计学意义(P<0.05)。结论重组脑利钠肽对急性心梗患者介入术后疗效较好,不良反应发生率较低。
Objective To investigate the effects of rhBNP on patients with AMI after PCI. Methods All of 60 patients with AMI after PCI were randomly divided into two groups （n = 30）： the research group（rhBNP）and control group （nitroglycerin）. Blood samples were collected at different time points to observe BNP. Acute Myocardial Infarction, heart failure within postoperative and 3 days. The volume of fluid intake and urine was recorded after drug administration. All patients re- ceived PCEA after surgery respectively. Results The counts of serum BNP, CK and CK-MB were significant different after PCI.The volume of fluid intake and urine and the side reactions were significant different （P 〈 0.05）. Conclusion rhBNP would have better effects and less side reactions on patients with AMI after PCI.
出处
《中国现代医生》
2012年第10期58-59,共2页
China Modern Doctor
基金
浙江省中医药管理局科技计划项目(2011CB073)
浙江省温岭市科技计划项目(2011WLCB0053)
