摘要
目的评价乌司他丁联合抗生素治疗急性胰腺炎致多器官功能损害的效果。方法将80例患者随机分2组(各40例),均给予禁食、营养支持与抗生素治疗,治疗组同时给予静脉滴注乌司他丁。结果治疗前两组患者的AMS、ALT、和CRP值无统计学差异;治疗后两组患者AMS分别为(18.5±2.5)IU/L和(22.4±3.3)IU/L,ALT分别为(31.6±4.8)U和(36.3±5.5)U,Cr分别为(72.1±7.2)μmol/L和(85.3±11.5)μmol/L,CRP分别为(6.4±2.6)mg/L和(8.3±3.4)mg/L,差异均有高度统计学意义(P均<0.01)。结论乌司他丁联合抗生素治疗急性胰腺炎致多脏器功能损害效果好,值得临床推广应用。
Objective To evaluate the effects of ulinastatin combined with antibiotics in the treatment of acute pancreatitis. Methods Eighty patients were randomly divided into two groups （40 patients in each group） and were given fasting, nu- tritional support and antibiotic treatment. At the same time, the treatment group was also given the intravenous infusion of ulinastatin. Results Before the treatment, the two groups of patients had no significant differences in AMS, ALT and CRP values. After the treatment, AMS of the two groups of patients was （18.5±2.5） IU/L and （22.4±3.3） IU/L respectively, ALT was （31.6±4.8） U and （36.3±5.5） U respectively, Cr was （72.1±7.2） μmol/L and （85.3±11.5） μmol/L respectively, CRP was （6.4±2.6） mg/L and （8.3±3.4） mg/L respectively, with statistical differences for all （P 〈 0.01）. Conclusion Ulinastatin com- bined with antibiotics in the treatment of acute pancreatitis-induced multiple organ impairment has good effects, thereby worthy of clinical promotion and application.
出处
《中国现代医生》
2012年第10期72-73,75,共3页
China Modern Doctor
关键词
急性胰腺炎
多脏器功能损害
血淀粉酶
谷丙转氨酶
肌酐
反应蛋白
乌司他丁
Acute pancreatitis
Multiple organ impairment
Hemodiastase
Alanine transferase
Creatinine
Reactive pro- tein
Ulinastatin
