摘要
目的:对比常规超声评价超声弹性成像(UE)在颈部淋巴结良恶性诊断中的价值。方法:对74例患者的99个淋巴结行灰阶超声(B超)、彩色多普勒血流图(CDFI)及UE检查。再行超声引导下穿刺活检,取得组织学病理结果作为最终诊断与B超、CDFI及UE进行对照。结果:在UE检查中,采用弹性应变率比值(Strain ratio,SR)法,以SR≥1.78作为颈部淋巴结的恶性诊断标准时,其灵敏度、特异度及准确度分别为98.3%,65.9%和84.8%;B超的灵敏度、特异度及准确度分别为55.2%,82.9%和66.7%;CDFI的灵敏度、特异度及准确度分别为72.4%,75.6%和73.7%。UE较B超具有更高的灵敏度、准确度及更大的ROC曲线下面积,且差异具有统计学意义(P<0.05);UE较CDFI具有更高的灵敏度,且差异具有统计学意义(P<0.05),但二者的ROC曲线下面积无统计学差异。结论:超声弹性成像中以SR 1.78为分界值对颈部淋巴结良恶性的鉴别诊断具有一定价值,与B超比较价值更大。
Objective： Comparing with conventional ultrasound,to validate the value of ultrasound elastography（UE） in differentiating benign and malignant cervical lymph node（LN）.Methods： B-mode ultrasound（B-US）,color Doppler flow image（CDFI） and UE were performed for 99 lymph nodes of 74 patients and compared with final histological pathology obtained by ultrasound guided core needle biopsy.Results： With the cutoff point of strain ratio（SR） ≥1.78 for malignancy,UE was the most valuable in differential diagnosis of benign and malignant cervical lymph nodes.The sensitivity,specificity and accuracy were 98.3%,65.9% and 84.8%.The sensitivity,specificity,accuracy of B-US and CDFI were 55.2%,82.9%,66.7% and 72.4%,75.6%,73.7%.Compared with B-US,the sensitivity,accuracy and area under the ROC curve（AUC） of UE were statistically higher.Compared with CDFI,UE had a statistically higher sensitivity,but not the AUC.Conclusion： SR with the cutoff point of 1.78 is better than B-US in the differential diagnosis of benign and malignant cervical lymph nodes.As conventional ultrasound,UE is expected to be an important technique in the differential diagnosis of benign and malignant cervical lymph nodes.
出处
《中国临床医学影像杂志》
CAS
2012年第3期157-160,共4页
Journal of China Clinic Medical Imaging
