摘要
目的 探讨血清PSA浓度变化与前列腺癌及其骨转移的相关性。 方法 对 93例直肠指诊异常及血清PSA >4ng/ml的患者 ,行直肠B超引导下前列腺穿刺活检 ;用 99mTc MDP行全身骨扫描判断有无骨转移。 结果 93例中前列腺活检阳性者 6 0例 (6 4.5 % ) ,其中 2 6例骨扫描阳性 ;随血清PSA浓度升高 ,前列腺阳性活检率及其远处骨转移阳性率升高 (P <0 .0 1)。结论 血清PSA升高与前列腺癌及其骨转移的发生率呈正相关。
Objective To evaluate the serum prostate specific antigen level in the detection of prostate cancer and skeletal metastasis. Methods Transrectal ultrasound guided needle biopsy of prostate was carried out for 93 subjects with an elevated serum PSA(>4.0ng/ml)and abnormal findings on rectal palpation.Whole body bone scintigraphy was undertaken for the detection of skeletal metastasis. Results 60(64.5%) of the 93 were diagnosed as prostatic cancer on biopsy of which 26 have had positive bone scan findings. Conclusions Prostate cancer and bony metastasis were more likely when serum PSA has been elevated.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2000年第4期229-231,共3页
Chinese Journal of Urology
