摘要
目的研究不同的胰岛索给药途径治疗初诊的2型糖尿病（T2DM）的疗效差异。方法将2009年1月至2011年6月在郑州大学第一附属医院住院的84例初诊T2DM患者按照自愿的原则分为胰岛素泵治疗组（CSⅡ）和皮下注射胰岛素组（MSⅡ）各42例。观察治疗后血糖变化、胰岛素用量、血糖达标时间、低血糖发生率及胰岛素泵停用后胰岛功能恢复情况。结果两组患者经治疗后血糖均明显下降。CSⅡ组与MSⅡ组相比较血糖更加容易平稳，血糖达标时间短，胰岛素用量偏少，低血糖发生率低，并且部分患者停泵后胰岛功能恢复较好，差异具有统计学意义。结论胰岛素泵治疗初诊T2DM疗效安全有效，适宜作为初诊2型糖尿病患者的首选治疗方法。
Objective To study the clinical effects of different insulin therapy type on newly di- agnosed type 2 diabetes. Methods Totally 84 patients with newly diagnosed type 2 diabetes were ran- domly assigned to continuous insulin infusion treatment group （CS Ⅱ group, 42 cases） and multiple sub- cutaneous insulin infusion treatment group （ MS Ⅱgroup, 42 cases） from January 2009 to June 2011. Blood glucose variation, insulin dosage, the time that blood glucose came up to the standards, the inci- dence of low blood glucose, and islet function when stopping the insulin pump therapy were observed. Results Blood glucose levels were lowered in both groups after treatment. But CS Ⅱ group was faster, and with lower insulin dosage, lower blood glucose fluctuation, lower rate of low blood glucose compared with MS Ⅱ groups. And some patients resumed the islet function. The differences were statistical significant. Conclusions It is secure and effective of insulin pump therapy in treating newly diagnosed type 2 diabetes, can be the first therapy method for newly diagnosed type 2 diabetes.
出处
《中国实用医刊》
2012年第9期5-6,共2页
Chinese Journal of Practical Medicine
关键词
胰岛素泵
皮下注射胰岛素
2型糖尿病
血糖
糖尿病强化治疗
Insulin pump
Subcutaneous insulin infusion
Type 2 diabetes
Blood glucose
Intensive treatment of diabetes
