摘要
目的 :从临床角度探讨一氧化氮 ( NO)在脑梗塞病人急性期中的作用机理。方法 :利用分光光度法及放射免疫分析法分别测定了脑梗塞病人急性期及恢复期血浆中的 NO、环 -磷酸鸟苷( c GMP)、降钙素 ( CT)、心钠素 ( ANP)的含量变化。结果 :脑梗塞病人急性期 NO及 c GMP、CT、ANP明显升高 ,NO与 c GMP、CT、ANP均呈显著正相关。结论 :NO在脑梗塞病人中具有双向作用
Objective To study the action of nitric oxide and correlative factors on the patients with cerebral infarction in acute stage.Methods The content of nitric oxide (NO) in the plasma of cerebral infarct patients was detected with spectrophotometry and the content of cyclic guanosine (cGMP),Calcitonin (CT),atrialnatriuretic polypeptide (ANP) in the plasma of cerebral infarct patients was detected with automatic radio immunity analysis.Results The level of NO,cGMP,CT and ANP in the plasma of cerebral infarct patients in acute stage was significantly higher than that in covalescent stage and in control.The level of NO was positively correlated to the level of cGMP,CT and ANP significantly.Conclusion NO has the two way action in the acute stage of cerebral infarct patients:Its base release dose has physiologic function and the excessive NO has neurotoxicity.
出处
《白求恩医科大学学报》
CSCD
2000年第1期39-41,共3页
Journal of Norman Bethune University of Medical Science
关键词
脑梗塞
一氧化氮
相关因素
急性
cerebral infarction
nitric oxide
correlative factors
