期刊文献+

肥胖与结合珠蛋白及脂联素相关性研究 被引量:1

The Level and Relationship between Haptoglobin and Adiponectin in Obesity Cases
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摘要 目的:探讨肥胖及正常人群中血清结合珠蛋白与脂联素之间的关系。方法:以酶联免疫法检测超重者、肥胖者和正常对照组各30例患者的结合珠蛋白水平,同时测定腰围、身高、体质量、脂联素等临床指标。结果:结合珠蛋白与脂联素呈负相关(r=-0.34,P<0.001);结合珠蛋白与体质量指数、腰围的相关性较脂联素明显。结论:结合珠蛋白与脂联素可能共同参与了肥胖的发病。 Objective:To investigate the relationship between haptoglobin and adiponectin in obese and healthy adults.Methods:We studied 90 adults including 30 obese,30 overweight,and 30 normal body mass index served as controls.The level of fasting serum Adiponectin,BMI,WC were uieasured.Results:There was a negative correlation between haptoglobin and adiponectin(r=-0.34,P0.001). The correlation between haptoglobin and BMI,WC is higher than the correlation with adiponectin.Conclusion:Haptoglobin and adiponectin play role in the mobidity of obesity.
出处 《中国医药导刊》 2011年第11期1841-1841,1843,共2页 Chinese Journal of Medicinal Guide
基金 黑龙江省卫生厅课题(2007-187) 哈尔滨医科大学附属第一医院院基金课题(2009Y25)
关键词 肥胖 结合珠蛋白 脂联素 体质量指数 Obesity Haptoglobin Adiponectin Body mass index(BMI)
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参考文献11

  • 1俞匀,朱大龙,徐小华,胡云,沈山梅,黄群.2型糖尿病患者一级亲属脂联素及三种细胞因子与胰岛素抵抗的相关性[J].中国糖尿病杂志,2006,14(4):247-249. 被引量:10
  • 2Hannerz J,Greitz D,Ericson K.Is there a relationship between obesity and intracranial hypertension?. International Journal of Obesity and Related Metabolic Disorders . 1995
  • 3Das UN.Is obesity an inflammatory condition. Nutrition . 2001
  • 4Visser M,Bouter LM,McQuillan GM,et al.Elevated C-reactive protein levels in overweight and obese adults. Journal of the American Medical Association, The . 1999
  • 5Bastard JP,Jardel C,Delattre J,et al.Evidence for a link between adipose tissue interleukin-6 content and serum C-reactive protein concentrations in obese subjects. Circulation . 1999
  • 6Maffei M,Halaas J,Ravussin E,et al.Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Medicine . 1995
  • 7Arita Y,Kihara S,Ouchi N,et al.Paradoxical decrease of an adipocyte specific protein, adiponectin, in obesity. Biochemical and Biophysical Research Communications . 1999
  • 8Fasshauer M,Klein J,Neumann S,et al.Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications . 2002
  • 9Bruun J M,Verdich C,Toubro S,et al.Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha.Effect of weight loss in obese men. European Journal of Endocrinology . 2003
  • 10Fantuzzi G.Adipose tissue, adipokines, and inflammation. Journal of Allergy and Clinical Immunology, The . 2005

二级参考文献10

  • 1庄向华,董砚虎,许爱梅,王娜,周建博,唐彬.糖尿病一级亲属脂联素和瘦素与胰岛素抵抗的相关性[J].中华糖尿病杂志(1006-6187),2005,13(1):8-10. 被引量:14
  • 2Yamamoto Y,Hirose H,Saito I,et al.Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol,independent of body mass index,in the Japanese population.Clin Sci (Lond),2002,103:137-142.
  • 3Senn JJ,Klover PJ,Nowak IA,et al.Interleukin-6 induces cellular insulin resistance in hepatocytes.Diabetes,2002,51:3391-3399.
  • 4Pellme F,Smith U,Funahashi T,et al.Circulating adiponectin levels are reduced in nonobese but insulin-resistant first-degree relatives of Type 2 Diabetic Patients.Diabetes,2003,52:1182-1186.
  • 5Fasshauer M,Klein J,Neumann S,et al.Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes.Biochem Biophys Res Commun,2002,290:1084-1089.
  • 6Ouchi N,Kihara S,Arita Y,et al.Adiponectin,an adipocytederived plasma protein,inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.Circulation,2000,102:1296-1301.
  • 7Fasshauer M,Kralisch S,Klier M,et al.Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes.Biochem Biophys Res Commun,2003,301:1045-1050.
  • 8Ouchi N,Kihara S,Funahashi T,et al.Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue.Circulation,2003,107:671-674.
  • 9何宗明,董砚虎.2型糖尿病一级亲属非糖尿病患者胰岛素抵抗与胰岛β-细胞功能状态的研究[J].中国慢性病预防与控制,2004,12(2):55-57. 被引量:3
  • 10朱大龙,胡云,韩光晓,顾经宇.2型糖尿病患者正常糖代谢一级亲属胰岛素抵抗及其相关因素分析[J].中国糖尿病杂志,2004,12(1):9-13. 被引量:11

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