摘要
轻度认知功能障碍（MCI）是老年性痴呆重要的危险因素之一，临床上对老年性痴呆干预疗效较差，对MCI的治疗效果较理想，因此，对MCI病因和发病机制的研究有极其重要的临床意义。研究表明，糖尿病可以造成脑组织结构和功能的损害，导致MCI。笔者课题组2011年12月在《Diabetes Care》发表了“2型糖尿病轻度认知功能障碍患者血清可溶性晚期糖基化终末产物受体水平及相关因素研究”，旨在揭示糖尿病与MCI的关系。
Mild cognitive impairment （MCI） is an important risk factor for Alzheimer＇ s disease. It is of great value to investigate the etiology and pathogenesis of MCI. Studies have shown that diabetes may cause damage to both the structure and function of brain tissue, resulting in MCI. We published one article in Diabetes Care titled ＂Serum level of endogenous secretory receptor for advanced glycation end products and other factors in type 2 diabetes patients with mild cognitive impairment＂ to elaborate the relationship between diabetes and MCI.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2012年第4期258-260,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
轻度认知功能障碍
可溶性晚期糖基化终末产物受体
Diabetes mellitus
Mild cognitive impairment
Endogenous secretory receptor for advanced glycation end products
