摘要
目的探讨多层螺旋CT(MSCTPI)灌注成像在肾脏良恶性肿瘤鉴别诊断中的应用价值。方法采用多层螺旋CT机对正常健康志愿者20例(对照组)及经手术病理证实的肾透明细胞癌患者22例(肾癌组)、肾错构瘤患者18例(肾错构瘤组)的肾皮质CT灌注参数进行检测,分别计算:灌注(perfusion);相对组织血容量(rBV);峰值时间(TTP);峰值增强影像(PEI)。结果①肾癌组的Perfusion、PEI值明显低于对照组,而rBV、TTP值明显高于对照组;②肾错构瘤组的Perfusion、PEI值明显低于对照组,而rBV、TTP值明显高于对照组;③肾癌组的perfusion、PEI值明显高于肾错构瘤组,而rBV、TTP值明显低于肾错构瘤组。结论多层螺旋CT灌注扫描技术能够较好地反映正常肾组织及肾脏良恶性肿瘤的血流动力学变化,为肾脏良恶性肿瘤的诊断与鉴别诊断提供可靠的依据,具有重要的临床应用价值。
Objective To discuss the clinical practice value of multi - slice spiral CT perfusion imaging in the differential diagnosis of benign and malignant renal tumors. Methods Using multi - slice spiral CT machine, we detected the CT perfusion parameters of 20 cases of normal healthy volunteers（the control group） ,22 cases of renal clear cell carcinoma proved by operation （the renal carcinoma group） and 18 cases of renal hamartoma（ the renal hamartoma group）. Perfusion （perfusion） , relative blood volume （rBV） , time to peak （TTP） and peak enhancementimage （PEI） were obtained and calaculated. Results （1）The perfusion,PEI of the renal carcinoma group were significantly lower than those of the control group, while the rBV,TTP were significantly higher than those of the control group; （2） The perfusion,PE1 of the renal hamartoma group were significantly lower than those of the control group, while the rBV ,TTP of the renal hamartoma group were significantly higher than those of the control group; （3）The perfusion,PEl of the renal carcinoma group were significantly higher than those of the renal hamartoma group, while the rBV,TTP of the renal carcinoma group were significantly lower than those of renal hamartoma group. The differences were significant statistically significant. Conclusion Multi - slice spiral CT perfusion imaging can quantitatively assess hemodynamics variation of the normal kidney,benign and malignant renal tumors. It can provide a reliable basis for differential diagnosis ,which has important clinical application value.
出处
《医学研究杂志》
2012年第4期125-127,共3页
Journal of Medical Research
