摘要
目的应用高频超声评价阿托伐他汀治疗颈动脉粥样硬化前后颈动脉血管变化,探讨其临床意义。方法应用高频超声对68例颈动脉粥样硬化斑块患者进行检查,观察其在阿托伐他汀治疗前后内膜中层厚度(IMT),斑块积分情况及斑块性质等变化。结果治疗组颈动脉内膜中层厚度显著变薄、斑块积分显著减低,不稳定斑块数目显著减少(P<0.05)。结论高频超声能准确监测颈动脉粥样情况,评价药物治疗效果,为临床心脑血管疾病的早期诊疗提供客观依据,减少脑梗死的发生。
Objective To explore the clinic significance of ultrasound in evaluation of carotid artery before and after treatment with atorvastatin in patients of atherosclerosis.Methods Sixty eight patients of carotid atherosclerosis were classified into two groups randomly.Patients in group A were treated with atorvastatin.,patients in group B were treated with placebo for one year.High frequency ultrasound was used to observer the intima-media thickness（IMT）,size and shape of plaques of carotid arteries of all the patients before and after treatment.Results The IMT,Crouse integral of plaques and number of unstable plaques were significant lesser after treatment in group A（P0.05）.Conclusion Atorvastatin is effective in treatment of carotid atherosclerosis.High frequency ultrasound was of great significance in diagnosis and treatment of carotid atherosclerosis.
出处
《当代医学》
2012年第13期45-46,共2页
Contemporary Medicine
