摘要
目的:探讨成人呼吸机相关性肺炎(VAP)的病因、发病率、病原学特点及其治疗。方法:回顾性分析我院2009年7月至2011年7月258例VAP患者临床资料,比较VAP的发生率、病原体、耐药性与治疗情况。结果:我院VAP的发生率为58%,258例VAP患者共检出349个微生物。79%为单一微生物感染,21%为多重微生物感染。病原体包括最常见的金黄色葡萄球菌(36.1%),铜绿假单胞菌(26.9%),不动杆菌(22.6%),肠杆菌属(9.2%),肺炎克雷伯杆菌(1.7%),假单胞菌(1.1%)。其中不动杆菌、铜绿假单孢菌、金黄色葡萄球菌耐药性高。结论:早期合理抗生素治疗VAP,可以降低VAP的死亡率,减少微生物的耐药性。
Objective： To investigate the etiology,incidence and resistance to antimicrobial agents,in patients with ventilator-associated pneumonia（VAP）.Methods：Clinical data of 258 cases of VAP from July 2009 to July 2011 in our hospital were analyzed retrospectively,and the incidence,pathogens,drug resistance and treatment of patients with VAP were compared.Results：The incidence of VAP in our hospital was 58%;349 microorganisms were detected in 258 cases of patients with VAP;the rate of single microorganism infection was 79%;the rate of multi-microbial infection was 21%.The most common pathogens were Staphylococcus aureus（36.1%）,Pseudomonas aeruginosa（26.9%）,Acinetobacter（22.6%）,Enterobacter spp（9.2%）,Klebsiella pneumoniae（1.7%）,and aeruginosa（1.1%）.Resistances of Acinetobacter,Pseudomonas aeruginosa bacteria,Staphylococcus aureus were high.Conclusion： Early reasonable antibiotic treatment of VAP can reduce the mortality rate of VAP and reduce antibiotic resistance.
出处
《泸州医学院学报》
2012年第2期216-218,共3页
Journal of Luzhou Medical College
关键词
呼吸机相关性肺炎
抗生素的耐药率
感染
Ventilator-associated pneumonia
Resistance to antimicrobial agents
Infection
