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帕瑞昔布钠超前镇痛在锁骨骨折术中的应用 被引量:3

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摘要 目的探讨帕瑞昔布钠超前镇痛用于锁骨骨折手术术后镇痛的临床效果。方法择期锁骨骨折手术60例,ASA分级I-II,随机分为两组。P组于手术前静注帕瑞昔布钠40mg,对照组(C组)于手术前20min静注生理盐水5ml。比较术后4、8、12、24h两组患者镇痛效果视觉模拟评分(VSA)以及患者的总体舒适度,同时记录两组患者首次要求镇痛的时间和追加镇痛的需求人数。结果两组患者的局麻药种类、浓度、剂量相同,手术时间比较无统计学差异。A组术后4、8、12、24hVSA评分均低于C组(P<0.05);A组患者首次要求镇痛的时间越长,哌啶镇痛的人次明显低于C组(P<0.05)。结论帕瑞昔布钠40mg超前镇痛能有效的减轻锁骨骨折术后的疼痛,值得推广。
作者 付江勇
出处 《江西医药》 CAS 2012年第3期255-255,273,共2页 Jiangxi Medical Journal
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  • 1徐建国.慢性疼痛的药物治疗进展[J].医学研究生学报,2007,20(2):113-115. 被引量:43
  • 2McArdle P. Intravenous analgesia. Crit Care Clin, 1999,15:89-104.
  • 3Bowdle TA. Adverse effects of opioid agonists and agonist-antagonists in anesthesia. Drug Saf, 1998,19:173-189.
  • 4Kehlet H, Dahl JB. The value of "multimodal" or "balanced analgesia"in postoperative pain treatment. Anesth Analg, 1993,77:1048-1056.
  • 5Power I, Barrett S. Analgesic agents for the postoperative period: nonopioids. Surg Clin North Am, 1999,79:275-295.
  • 6Tong D, Chung F. Postoperative pain control in ambulatory surgery. Surg Clin North Am, 1999,79:401-430.
  • 7Lipsky LP, Abramson SB, Crefford L, et al. The classification of cyclooxygenase inhibitors. J Rheumatol, 1998,25:2298-2303.
  • 8Penning TD, Talley JJ, Berteushaw SR, et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenuse-2 inhihitors:identification of 4- [ 5- ( 4-methylphenyl ) -3- ( trifluoremethyl )- 1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). J Med Chem, 1997,40:1347-1365.
  • 9Tang J, Li S, White PF, et al. Effect of parecoxib, a novel intravenous cyclooxygenuse type-2 inhibitor, on the postoperative opioid requirement and quality of pain control. Anesthesiology, 2002,96: 1305-1309.
  • 10Malan TP Jr,Marsh G, Hakki SI, et al. Parecoxib sodium, a parenteral cyclooxygenuse 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty. Anesthesiology, 2003,98 :950-956.

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