摘要
目的观察带结膜瓣角膜缘干细胞移植术治疗翼状胬肉的疗效。方法用回顾性分析方法研究该院自2006年4月～2009年9月91例(102眼)翼状胬肉患者,依照采取不同手术方式分为两组:A组翼状胬肉单纯切除术34眼(均为原发);B组带结膜瓣角膜缘干细胞移植术68眼(57例共68眼,双眼11例,65眼原发,3眼复发)。所有患者术后随访为3～12月。术后观察结膜角膜修复情况、手术后并发症及胬肉复发情况,评价其疗效。统计学分析两组手术方法的效果差异。结果两组手术方法的术后复发率比较:翼状胬肉单纯切除术组4眼复发,复发率为11.76%;带结膜瓣角膜缘干细胞移植术治疗翼状胬肉术组无复发,复发率为0。两组均没有严重威胁到手术患者的视功能的并发症。结论两组手术方法的结果比较表明,带结膜瓣角膜缘干细胞移植术治疗翼状胬肉组较翼状胬肉单纯切除术组复发率低。
Objective To observe with conjunctival limbal stem cells transplantation in treatment of pterygium.Methods Retrospective analysis was made of our hospital from April 2006 to September 2009.Ninety-one patients（102 eyes） of pterygium patients,according to different operation mode,were divided into two groups：group A simple excision of pterygium in 34 eyes（primary）,group B with conjunctival flap transplantation of corneal limbal stem cell in 68 eyes（a total of 57 cases 68 eyes of 11 cases,65 eyes,primary and 3 eyes recurrent）.All patients were followed up for 3 months to 1 year.Postoperative observation of was made of conjunctival and corneal repair after operation,complication and recurrence of pterygium,and its curative effect was evaluated.Statistical analysis of two operation methods was made on the effect difference.Results By comparing operation method and postoperative recurrence rate,simple excision of pterygium group had 4 eyes recurred,the recurrence rate being 11.76%,while conjunctival limbal stem cells transplantation in treatment of pterygium surgery group had no relapse,recurrence rate being 0.Both groups had no complications which seriously threat the visual function of the patients.Conclusion It shows that with conjunctival limbal stem cells transplantation in treatment of pterygium group has a lower recurrence rate than the simple excision of pterygium group.
出处
《安徽医药》
CAS
2012年第3期333-334,共2页
Anhui Medical and Pharmaceutical Journal
关键词
翼状胬肉
结膜瓣角膜缘
干细胞
移植
pterygium
limbal conjunctival flap
stem cells
transplantation
