摘要
目的探讨热毒宁治疗小儿麻疹合并肺炎的临床疗效及安全性。方法将126例麻疹合并肺炎患儿采用随机数字表法分为治疗组和对照组各64例。在西医常规治疗基础上,治疗组加用热毒宁治疗,对照组加用利巴韦林治疗。通过退热时间、咳嗽和咯痰缓解时间、啰音消失时间、X线片影消失时间、白细胞复常时间、皮疹完全结痂时间、住院时间评价临床疗效,对2组临床疗效及不良反应进行比较。结果治疗组有效率为96.88%,高于对照组的84.38%;退热时间、咳嗽和咯痰缓解时间及住院时间等观察指标均短于对照组,差异有统计学意义(P<0.05)。治疗组不良反应发生率为9.38%,对照组为10.94%,2组比较差异无统计学意义(P>0.05)。结论热毒宁治疗小儿麻疹合并肺炎具有良好的疗效,不良反应少,安全性高,值得临床推广应用。
Objective To discuss the efficacy of Reduning in treating of pediatric measles merger pneumonia,and ob- serve the safety. Methods 126 children with pneumonia were randomly divided into the treatment group and control group （64 in each）, the control group was given ribavirin injection and conventional symptomatic treatment, the treatment group was given the with Chinese traditional medicine of Reduning injection based onroutine treatment, By comparing the two groups in antifebrile time, cough sputum ease time, rales disappear time, X-ray disappear time, hospital stays, White blood cells resume normal time, Blood biochemical index returned to normal time, the eruption completely scabby time to contrast the treatment effect, observe the adverse drug reaction in the process. Results The effective rate of treatment group was higher than the con- trol group（96.88% vs 84.38%, P 〈 O. 05 ）, antifebrile time, cough sputum ease time, rales disappear time, X-ray disappear time, hospital stays, White blood ceils resume normal time, Blood biochemical index returned to normal time, the eruption com- pletely scabby time were significantly less than the control group （P 〈 0.05 ）, and all are statistically significant differences. Treatment of adverse reaction rate compared with the control has no significant difference （9.38% vs 10.94%, P 〉 0.05 ）. Conclusion Reduning has good effect in treating of pediatric measles merger pneumonia, fewer side effects, high safety, it is worth promoting use in clinic.
出处
《临床合理用药杂志》
2012年第14期19-20,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
麻疹
小儿
肺炎
热毒宁
疗效
不良反应
Pediatric measles
Pneumonia
Reduning Injection
Clinical effect
Adverse reaction
