摘要
目的:对补骨脂的超临界CO2流体萃取工艺条件进行优化。方法:选取萃取温度、萃取压力、萃取时间为考察因素,以补骨脂素和异补骨脂素萃取率为指标,采用单因素考察及正交试验对补骨脂萃取工艺进行优选。结果:优选的工艺条件为1.5倍量95%乙醇为夹带剂,萃取温度65℃,萃取压力20 MPa,萃取时间2 h。结论:优选的超临界CO2流体萃取工艺合理,可行。
Objective： To optimize extraction technology condition of Psoralea corylifolia by supercritical CO2fluid extraction. Method： Single factor test and orthogonal test were used to optimize extraction technology of P. corylifolia with extraction ratio of psoraIent and isopsoralent as indexes, extraction temperature, extraction pressure and extraction time were taken as factors. Result： Optimum extraction conditions were as follows： 1.5 times the amount of 95% ethanol as entrainer, extraction temperature was 65 ℃, extraction pressure was 20 MPa, extraction time was 2 h. Conclusion： This optimized technology of supercritical CO2 extraction was reasonable and feasible.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第10期44-46,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
江苏省高校优势学科建设工程项目
