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尿酸与非酒精性脂肪肝血管内皮损伤的相关性

The association between serum uric acid and endothelial dysfunction in non-alcoholic fatty liver disease
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摘要 非酒精性脂肪肝的血管内皮功能损伤的发病机制可能与高尿酸血症有关。高尿酸血症可通过各种途径如氧化应激、炎症反应等引起非酒精性脂肪肝的血管内皮损伤，进而导致心血管疾病，其中心环节是胰岛素抵抗。 The pathogenesis of endothelial dysfunction in non-alcoholic fatty liver disease may be asso- ciated with hyperuricemia. Hyperuricemia can induce endothelial dysfunction in non-alcoholic fatty liver disease through various pathways such as oxidative stress, inflammation, and then results in cardiovascular disease, but the core is insulin resistance.
作者 廖海菊（综述） 刘戈力（审校）
机构地区 天津医科大学总医院儿科
出处 《国际儿科学杂志》 2012年第3期280-283,共4页 International Journal of Pediatrics
关键词 非酒精性脂肪肝 血管内皮损伤 高尿酸血症 心血管疾病 胰岛素抵抗 Non-alcoholic fatty liver disease Endothelial dysfunction Hyperuricemia Cardiovascular disease Insulin resistance
分类号 R575.5 [医药卫生—消化系统]
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参考文献30

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国际儿科学杂志
2012年 第3期

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