摘要
目的评估北京市HIV感染者及AIDS患者(PLWHA)生存质量状况及其影响因素。方法于2010年9—12月间,采用方便抽样法选取现居住于北京市的PLWHA共310例,通过一般情况问卷、SF-36生存质量量表和Berger—HIV耻辱量表对其进行调查,采用t检验、多元线性回归等方法对调查结果进行分析。结果调查对象年龄为(32.87±8.76)岁,感染途径以同性性行为为主(84.52%,262/310)。SF-36生存质量总分为(66.75±15.70)分,躯体功能、躯体角色、躯体疼痛、总体健康、活力、社会功能、情感角色、心理健康8个维度得分分别为(93.00±9.49)、(66.53±40.26)、(73.88±22.63)、(50.06±22.75)、(61.11±19.67)、(69.50±24.24)、(59.68±42.38)、(60.63±19.81)分。除躯体功能维度外,PLWHA的生存质量各维度得分均低于常模(P〈0.05)。多元回归分析结果显示,耻辱感越高,生存质量总分[标准化偏回归系数(β’)=-0.38]、躯体角色(β’=-0.21)、躯体疼痛(β’=-0.13)、总体健康(β’=-0.33)、活力(β’=-0.31)、社会功能(β’=-0,34)、情感角色(β’=-0.31)、心理健康(β’=-0.47)得分越低(P值均〈0.05);治疗AIDS及相关疾病花费越高,生存质量总分(β’=-0.17)、躯体功能(β’=-0.28)、躯体角色(β’=-0.15)、躯体疼痛(β’=-0.19)、总体健康(β’=-0.15)、社会功能(β’=-0.11)、情感角色(β’=-0.16)得分越低(P值均〈0.05);有工作者生存质量总分(β’=0.13)、躯体功能(β’=0.13)、躯体角色(β’=0.12)、躯体疼痛(β’=0.12)、活力(β’=0.13)、社会功能(β’=0.12)、情感角色(β’=0.12)高于无工作者(P值均〈0.05)。结论PLWHA的生存质量较低,耻辱感强、治疗费用高、无工作等是主要不利因素。
Objective To assess the quality of life of people living with HIV or AIDS (PLWHA) and to identify influencing factors. Methods During September to December 2010, by a convenience sampling, a questionnaire survey was undertaken in 310 PLWHA living in Beijing, which included the general questionnaires, SF-36 for assessing quality of life and Berger-HIV stigma scale. T test and muhivariable linear regression model were used to analyze the results. Results For the subjects investigated, the age was (32. 87 ± 8.76 ) years old. Homosexual behavior was the main dissemination ( 84. 52%, 262/310 ) . The results of SF-36 questionnaire were : the summary score 66. 75 ± 15.70 ; physical function 93.00 ± 9.49, role physical 66. 53 ± 40. 26,bodily pain 73.88 ± 22. 63, general health 50. 06 ± 22. 75, vitality 61.11 ± 19.67, social function 69. 50 ± 24. 24,role emotional 59. 68 ± 42. 38, mental health 60. 63 ± 19. 81. Except physical functioning, the scores of every scale were lower than general persons ( P 〈 0. 05 ) . Muhivariable linear regression analysis showed that the stronger stigma, the lower the summary score (standardized coefficients (β') = -0. 38 ), role physical (β' = - 0. 21 ), bodily pain (β'= - 0. 13 ), general health (β' = - 0. 33 ), vitality(β' = - 0. 31 ) , social function (β' = - 0. 34 ), role emotional (β' = - 0. 31 ), mental health (β' = -0. 47) ( all P values 〈 0. 05 ). The higher expend on treating HIV, the lower the summary score (β' = - 0. 17 ) , physical function(β' = - 0. 28 ) , role physical (β' = - 0. 15 ), bodily pain (β' = - 0. 19 ), general health (β' = - 0. 15 ), social function (β' = - 0. 11 ), role emotional (β' = - 0. 16 ) ( all P values 〈 0. 05 ). Who having work got higher score in the summary score (β' = 0. 13 ), physical function (β' = 0. 13 ), role physical(β' = 0. 12 ), bodily pain (β' = 0. 12 ), vitality (β' = 0. 13 ), social function (β' = 0. 12 ), role emotional(β' = 0. 12) than others (all P values 〈 0. 05 ). Conclusion The quality of PLWHA's life was low. High stigma feeling, high expend on treating HIV, having a job were the main influencing factors of quality of life in PLWHA.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2012年第6期514-518,共5页
Chinese Journal of Preventive Medicine
基金
基金项目:中国卫生部-比尔及梅琳达盖茨基金会艾滋病防治合作项目
北京市科技计划(1309050703590902)
关键词
HIV
生活质量
因素分析
统计学
HIV
Quality of life
Factor analysis, statistical