摘要
目的:探讨膝周神经射频热凝联合玻璃酸钠注射治疗顽固性膝骨关节炎疼痛的临床效果。方法:36例严重膝骨关节炎疼痛的患者,共57个患膝,随机分为两组:射频加玻璃酸钠组(R组),行膝周神经射频热凝加关节腔内玻璃酸钠注射;对照组(C组),单纯关节腔内玻璃酸钠注射。分别于治疗前、治疗后1周、治疗后6周和治疗后12周,记录患者疼痛视觉模拟评分(visual analoguescale,VAS)、患者对治疗效果综合评估(patient's global assessment,PGA)和不良反应。结果:治疗后的12周内,R组VAS评分显著低于C组。R组PGA在第1周和第12周均显著高于C组。所有患者均未发生明显的不良反应。结论:膝周神经射频热凝联合玻璃酸钠注射治疗顽固性膝骨关节痛效果明显,安全可靠,可成为治疗老年性膝骨关节炎的有效手段。
Objective： To investigate the effects of genicular nerve radiofrequency ablation combined with intra-articular injection of sodium hyaluronate on the treatment of refractory knee osteoarthritic pain.Methods： 36 elderly patients with severe knee osteoarthritic pain（total 57 knees） were randomly assigned into two groups： treatment group（group R） and control group（group C）.Group R received genicular nerves radiofrequency ablation and intra-articular injection of sodium hyaluronate.Group C received intra-articular injection of sodium hyaluronate only.Visual analogue scale（VAS） and patient’s global assessment（PGA） were measured at before treatment,1 week,6 weeks,and 12 weeks after treatment.Results： Compared with the group C,knee pain decreased significantly in group R at 1 week,6 weeks,and 12 weeks after treatment.Compared with the group C,PGA increased significantly in group R at 1 week and 12 weeks after treatment.No serious adverse effect appeared in this study.Conclusion： Genicular nerve radiofrequency ablation combined with intra-articular injection of sodium hyaluronate can reduce the pain and improve the function of the knee.It may be a promising method for elderly knee osteoarthritis pain.
出处
《中国疼痛医学杂志》
CAS
CSCD
北大核心
2012年第6期322-324,共3页
Chinese Journal of Pain Medicine
关键词
慢性膝骨关节疼痛
膝周神经
射频热凝
Chronic knee osteoarthritic pain
Genicular nerve
Radiofrequency ablation
