摘要
[目的]探讨早发型重度子痫前期的母儿结局及期待治疗的可行性.[方法]回顾分析性分析早发型重度子痫前期109例患者,根据发病孕周分为三组：小于30周42 例（A组）,30～31＋6周28例（B组）,32～33＋6周39例（C组）.比较三组期待治疗的时间,孕妇并发症及围产儿结局.[结果]三组孕妇期待治疗时间A组〉B组〉C组,组间比较差异有统计学意义（P〈0.05）;早发型重度子痫前期孕妇发病越早,围生儿死亡率越高,差异有统计学意义（P〈0.05）;三组孕妇并发症的发生率比较差异无统计学意义（P〉0.05）.[结论]早发型重度子痫前期病情重,并发症发生率高,围生儿预后差,其母儿结局与发病孕周密切相关,可在严密的母婴监护确保母婴安全的前提下行期待疗法.
[Objective]To explore the maternal and neonatal outcome of earl-onset severe preeelampsia and the feasibility of expectant treatment. [Methods]A total of 109 patients with early-onset severe preeelamp-sia were analyzed retrospectively. According to gestation age at onset, all patients were divided into 3 weeks. The gestation age of group A（ n=42） was lower than 30 weeks, and that of group B（ n=28） was 30-31 weeks, and that of group C（ n=39） was 32-33 weeks. The time of expectant treatment, pregnant compila-tions and perinatal outcome were compared among 3 groups. [Results] The time of expectant treatment time in group A was longer than that in group B, and that in group B was longer than that in group C, and there was significant difference among 3 groups（ P 〈0.05）. The earlier the onset time of early-onset severe preeclamp-sia, the higher the perinatal mortality, and there was also significant difference（ P 〈0.05）. There was no sig-nificant difference in the incidence of pregnant complications among 3 groups（ P〉0.05）. [Conclusion] Early-onset severe preeclampsia has serious condition, high pregnant complications and poor perinatal prognosis. Maternal and neonatal outcome of early onset severe preeclampsia is closely related to gestational age at onset. Expectant therapy should be adopted under intensive surveillance and care for ensuring the safe of mother and infant.
出处
《医学临床研究》
CAS
2012年第5期931-933,共3页
Journal of Clinical Research
