摘要
目的探讨急性冠脉综合征(ACS)患者血清同型半胱氨酸(Hcy)水平与冠状动脉病变程度的关系及临床意义。方法 60例急性冠脉综合征患者作为研究组(包括急性心梗组30例、不稳定型心绞痛组30例),30例健康体检者作为对照组。所有人均取外周静脉血检测血清同型半胱氨酸(Hcy),分析血清同型半胱氨酸(Hcy)水平与Gensini评分的关系。结果与对照组比较,研究组Hcy明显增高,差异有统计学意义(P<O.01)。急性心肌梗死组与不稳定型心绞痛组Gensini评分差异具有统计学意义(t=4.14,P<0.01)。相关性检验显示ACS患者Hcy水平与Gensini评分成正相关(r=0.683,P<0.01)。结论 ACS患者血清Hcy水平与冠状动脉病变程度密切相关。
Objective To investigate the correlation of homocystein（Hcy） in serum with Gensini score in patients with acute coronary syndrome（ACS）.Methods Sixty patients with ACS were enrolled in this study,including 30 patients with acute myocardial infarction（AMI） and 30 patients with unstable angina pectoris（UAP）.Thirty healthy subjects were chosen as control group.The lesions of coronary arteries were assessed.The relation of the serum level of Hcy with Gensini score was analyzed.Results The level of Hcy in serum was higher in patients with ACS than that in controls（P〈0.05）.Gensini score was significantly higher in AMI group than in UAP group（t=4.14,P〈0.01）.The level of Hcy was positively related with Gensini score in ACS patients（r=0.683,P〈0.01）.Conclusion Serum level of homocystein in patients with ACS is closely related to the atherosclerotic lesions of coronary arteries.
出处
《山西医科大学学报》
CAS
2012年第6期441-444,共4页
Journal of Shanxi Medical University
