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糖化血红蛋白检测的局限性 被引量:14

The detection of hemoglobin Alc in clinical application
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摘要 HbA1c测定结果能够反映患者最近2~3个月内的平均血糖水平,其临床应用价值正从“评估指标”向“诊断指标”转变。由于HbA1c检测受多种因素影响,其标准化进程在我国起步较晚,“切点”问题以及HbA1c在分子水平存在“缺陷”等,限制了HbA1c作为糖尿病诊断指标的应用。因此,阐明HbA1c在实际应用中的局限性对于其更好地应用于临床具有重要的意义。 The hemoglobin Alo (HbAlo) results can reflect the average level of blood glucose over the past 2-3 months, its clinical application value is transforming from evaluation indicator to diagnosis indicator. The application of HbAlo as a diagnostic indicator of diabetes is limited by many factors, such as muhi-factor influence on measurement and its late start on standardization process in our country, optimal cut-point and the defect of HbAlc existing in the molecular level, etc. Therefore, clarifying the limitations of HbAlc in the practical application is of great significance for its clinical application.
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2012年第6期501-504,共4页 Chinese Journal of Laboratory Medicine
关键词 糖尿病 血红蛋白A 糖基化 Diabetes mellitus Hemoglobin A, glycosylated
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同被引文献142

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