摘要
以二乙酰基二茂铁为原料,合成了二乙酰基二茂铁二肼腙,继而将其与丙酮反应合成了目标产物丙酮缩二乙酰基二茂铁二肼腙Schiff碱.中间体及目标产物的结构经IR、1 H NMR及元素分析得以确证.通过体外抑菌活性研究结果表明,目标产物对大肠杆菌(E.Coli),金黄色葡萄球菌(S.Aureus),枯草杆菌(B.Subtilis)均有较好的抑菌活性.
Diacetylferrocene dihydrazone was synthesized by diacetylferrocene and hydrazine; then acetone diaeetylferrocene dihydrazone schiff base was obtained by acetone and diacetyl- ferrocene dihydrazone. The structures of intermediate and the product were confirmed by IR, 1H NMR and elemental analysis. Initial activity evaluation of intermediate and the prod- uct indicated that the product had better antibacterial activity to E. Coli ,S. Aureus and B. Subtilis.
出处
《陕西科技大学学报（自然科学版）》
2012年第3期54-57,共4页
Journal of Shaanxi University of Science & Technology
基金
陕西省自然科学基础研究计划重点项目(2009JZ002)
