摘要
研究比较左氧氟沙星 (L VL X)与头孢曲松 (CRO)治疗老年细菌性下呼吸道感染的临床疗效和安全性。 5 6例病人随机分为试验组 (L VL X) 2 7例 ,2 0 0 mg静脉滴注每日 1次 ;对照组 (CRO) 2 9例 ,2 g静脉滴注 ,每日 1次 ,疗程均为 7～ 10 d。评价其临床疗效及安全性 ,结果 ,试验组与对照组的临床总有效率和不良反应分别为 (85 .18% )、(7.4% )和 (89.6 6 % )、(4.16 % ) ,两组差别无显著性 (P>0 .0 5 )。提示左氧氟沙星与头孢曲松在治疗老年细菌性下呼吸道感染上具有相同的疗效及安全性。
To evaluate the curative effect and safety of levofloxacin and ceftriaxone in aged patients with bacterial lower respiratory infection. Fiftysix aged patients with bacterial lower respiratory infection were randomly divided into test group (27 cases) and control group (29 cases). Patients of test group were treated with levofloxacin, 200mg iv drip/d; patients of control group with ceftriaxone, 2g iv drip /d. The overall effective rate and side effect rate of two group were 85.18%, 7.4% and 89.66%, 4.16% respectively, there was no statistical difference between two groups ( P >0.05). Levofloxacin and ceftriaxone have similar curative effect and safety in the treatment of aged patients with bacterial lower respiratory infections.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2000年第2期158-160,共3页
Chinese Journal of Antibiotics
关键词
左氧氟沙星
头孢曲松
下呼吸道感染
老年人
Levofloxacin
Ceftriaxone
Bacterial respiratory infection in the elderly
Efficacy
Safety
