摘要
目的了解重型β地中海贫血（地贫）儿童输血不良反应的发生率及发生类型的分析。方法对选取的142例反复输血的重型β地贫儿童的1220次输血进行输血不良反应的类型和发生率进行分析。结果重型β地贫不良反应的阳性率为2．79％，具体分布：皮疹11例（32．4％），发热9例（26．5％），皮肤红加瘙痒5例（14．7％），发热加皮疹3例（8．8％），发热加紫癜2例（5．9％），皮肤红2例（5．9％），烦躁1例（2．9％），瘙痒1例（2．9％）。结论反复输血的重型β地中海贫血患儿输血不良反应以发热与不同类型的过敏症状为主，多次出现不良反应建议输洗涤红细胞。
Objective To explore the positive rate and special types of adverse transfusion reaction in children with severe βthalassema{βthal} with different genotype. Methods Clinical information from 142 children with β thai（doub- le heterozygote or homozygote} who had suffered blood transfusion repeatedly was analyzed then followed with the calculation of the positive rate as well as constituent ratio for every special type of irregular antibodies. Results The incidence of adverse transfusion reaction in 142 children with βthai who had suffered blood transfusion for totally 1220 times was 2.79 %. The constituent ratio was displayed as follows：skin rash accounted for 32.4%, fever accounted for 26.5 %, skin rash accompanied with skin itching accounted for 14.7 %, skin rash accompanied with fever accounted for 8.8% ,peliosis accompanied with fever accounted for 5.9%, dysphoria and skin itching only accounted for 2.9 %, respectively. Conclusions Fever as well as all kinds of allergy symptoms are main types of adverse transfusion reaction in children with β thai who have suffered blood transfusion repeatedly. It is suggested that washed red blood cells be the first choice of blood products for children with β0 thal.
出处
《中国误诊学杂志》
CAS
2012年第14期3488-3489,共2页
Chinese Journal of Misdiagnostics
基金
1.广州市卫生局资助项目（2007-YB-220）
2.广东省卫生厅资助项目（A2003658）
