摘要
目的探讨辛伐他汀对原发性高血压并发急性脑梗死患者血清C反应蛋白(CRP)的影响。方法将原发性高血压患者发生急性脑梗死患者47例随机分为观察组和对照组,两组患者均进行常规调节血压、血糖,抗凝,抗血小板,改善微循环等治疗,研究组在此基础上加用辛伐他汀20 mg/d。结果原发性高血压并发急性脑梗死患者的血清CRP水平均有不同程度升高。经过治疗,观察组和对照组的血清CRP均有下降,但观察组下降更明显,两组相比差异有统计学意义。结论辛伐他汀具有显著降低原发性高血压并发急性脑梗死患者血清CRP水平的作用。
Objective To investigate the effect of simvastatin on C-reaction protein（CRP） in the patients with essential hypertension complicating acute cerebral infarction.Methods 47 patients with essential hypertension complicating acute cerebral infarction were randomly divided into two groups.Both groups were given the routine treatment of regulating blood pressure and blood sugar,anticoagulation and antiplatelet and improving microcirculation.On this basis,the study group was added simvastatin 20 mg/d.Results Serum CRP in the patients with essential hypertension complicating acute cerebral infarction was increased to different degrees.After treatment,CRP in both the two groups was dropped,but the decrease in the observation group was more obvious,difference between the two groups showed statistical significance.Conclusion Simvastatin has the role to significantly decrease the CRP level in essential hypertension complicating acute cerebral infarction.
出处
《现代医药卫生》
2012年第12期1797-1797,1799,共2页
Journal of Modern Medicine & Health
关键词
C反应蛋白质
辛伐他汀
脑梗死
高血压
C-reactive protein
Simvastatin
Brain infarction
Hypertension
