摘要
目的本研究旨在寻找一种简便可靠的诊断ＨＰ新方法。方法采用生化分析法测定了１００例经病理切片染色法 检出的各级ＨＰ感染患者空腹胃液氨浓度。结果：ＨＰ（－）２８例（１０．９７±２．３３ｍｍｏｌ／Ｌ，ＨＰ（＋）２８例（２１．９６±６．９８ｍｍｏｌ／Ｌ），ＨＰ （＋＋）３２例（３１．７９±１３．５４ｍｍｏｌ／Ｌ），ＨＰ（＋＋＋）１２例（４５．６８±１６．２３ｍｍｏｌ／Ｌ）组间差异（Ｐ＜０．０１）有非常显著意义。以１３、２９、 ４５ｍｍｏｌ／Ｌ为上限诊断ＨＰ（＋）（＋＋）（＋＋＋）感染，其敏感性分别为７８．６％，８７．５％，１００％，特异性分别为８７．３％，８９．５％，９２．８％。 故可作为定量诊断整体胃粘膜ＨＰ感染程度的一个有效指标。
Objective The aim of the study is to find a new, simple and reliable mthod to dignose HP. Methods The concentration of NH^+_4 in gastric fluid of 100 patients with HP was detected by biochemical analysis, which were determined by histological stain examination. Results HP(-) was in 28 cases (10.97 +2. 3 3mmol / L);HP (+ ) was in 28 cases (21 .96 +6. 98mmol/L);HP (++) was in 32 cases (31.79+13.54mmol/L);and HP (+++) was in 12 cases (45.68+16.23mmol/L). The diffterence among groups was significant. The upper lines of diagnosis of HP infection (+), (++), (+++) were 13mmol/L, 29mmol/L and 45mmol/L respectively. The sensitivities were 78.6%,87.5% and 100% respectively, and the specificities were 87.3%,89.5% and 92.8% respectively. So the method can be used as an effective standard for detection of HP infec- tion in the whole gstric mucosa.
出处
《中国实验诊断学》
2000年第2期63-64,共2页
Chinese Journal of Laboratory Diagnosis
基金
吉林省科委应用基础基金!(970564-1)
关键词
幽门螺杆菌
胃液氨
空腹胃液
组织染色法
Helicobacter pyloir
NH_4^+ in gastric fluid
Fasting gastric fluid
Histological stain method
