摘要
目的 探讨急性、慢性肝炎血清总胆汁酸（ＴＢＡ）测定的可能作用。方法 经肝穿刺活检病理证实为急性、慢性病毒性肝炎９２ 例，对ＴＢＡ含量进行了测定，并与ＡＬＴ及Ｔｂｉｌ进行对比分析。结果 急性肝炎与慢性肝炎ＴＢＡ与正常组比较有显著性差异（Ｐ均＜ ０．００１），慢性肝炎轻、中、重型三组ＴＢＡ经χ２ 和ｔ检验，各组比较无显著性差异（Ｐ＞ ０．０５）。结论 急性肝炎时ＴＢＡ检测与ＡＬＴ同样具有高度灵敏性，在慢性肝炎ＴＢＡ敏感性明显高于ＡＬＴ及Ｔｂｉｌ的检测，但并不能准确反映肝脏病变轻重。
Objective To study the probable function of serum total bile acid in diagnosis of hepatitis.Method The contents of total serum bile acid were detected in 92 cases of acute and chronic hepatitis confirmed by needle biopsy,being compared with alanine transaminase and total bilirubin.Results TBA had significant different between acute and chronic group and normal group ( P <0.001).The abnormal rate of TBA had no significant difference in mild,moderate,severe hepatitis.Conclusion TBA detection was high sensitive as well as ALT in acute hepatitis.In chronic hepatitis,the sensitive of TBA detection was very higher than those of ALT and Tbil detection.But it couldn't reflect exactly the cxtent of eepatitis. [
出处
《临床内科杂志》
CAS
2000年第1期44-45,共2页
Journal of Clinical Internal Medicine
关键词
病毒性肝炎
胆汁酸
血清诊断
Viral hepatitis/diagnosis
Bile acid
Alanine transaminase
Bilirubin
