摘要
胆管癌(cholangiocarcinoma,CC)是相对罕见的胆道恶性肿瘤,近年来,全球发病率、死亡率显著增加,但由于治疗手段有限,有效的根治性切除率低,且术后肿瘤复发率较高,治疗仍是一个挑战。随着人们对其生物学特性的深入研究以及诊断技术的进步,其治疗观念及方法也在不断地更新,比如肝移植、基因治疗等,文中将对CC的治疗及其现状作一综述。
Cholangiocarcinoma is a devastating cancer with increasing incidence and mortality worldwide. Challenges remain to the treatment of the disease for limited strategies, low effectiveness rate of complete surgical resection, and high rate of postoperative recurrence. Recently, deeper insights into the bio-characteristics of the disease have given birth to some new therapeutic concepts and methods, such as liver transplantation and gene therapy.
出处
《医学研究生学报》
CAS
北大核心
2012年第5期520-523,共4页
Journal of Medical Postgraduates
基金
江苏省卫生科研项目(H200835)
关键词
胆管癌
R0切除
肝移植
光动力治疗
基因治疗
Cholangiocarcinoma
R0 resection
Liver transplantation
Photodynamic therapy
Gene therapy