摘要
目的探讨早发型子痫前期肾病综合征的临床特点、并发症及其对母婴的影响。方法对35例早发型子痫前期肾病综合征患者(NSP组)与同期98例早发型重度子痫前期患者(对照组)进行回顾性比较分析。结果NSP组24 h尿蛋白量以及腹水、肾功能受损、小于胎龄儿、新生儿并发症等患病率与对照组之间均有显著性差异(P<0.01)。NSP组围产儿死亡率高于对照组,两组间有显著性差异(P<0.01)。结论 NSP病情严重,围产期的母婴预后不佳,应给予综合治疗,并需要严密监测母婴病情,适时终止妊娠以改善母婴预后。
Objective ： To study the clinical feature and complication of nephrotic syndrome with early onset preeclampsia and their effects on mothers and infants. Methods ： Thirty-five eases of nephrotic syndrome with early onset preeelampsia （NSP group） were retrospectively analyzed and compared with 98 cases of early onset severe preeelampsia （control group） in the past 5 years. Results： There were significant differences in the prevalence rate of proteinurla, hydrogaster, the impairment of renal function, small size-for-gestational-age infants and the neonatal complication between NSP group and control group （ P 〈 0.01 ）. The perinatal mortality was higher in NSP group than in control group （ P 〈 0.01 ）. Conclusion ： The patient＇s conditions of NSP are serious and the perinatal maternal and fetal prognoses are not good. Obstetricians should give combined therapy and close monitoring to the perinatal mothers and infants. Timely termination of pregnancy is helpful in improving their prognoses.
出处
《泰山医学院学报》
CAS
2012年第4期264-266,共3页
Journal of Taishan Medical College
关键词
早发型子痫前期
肾病综合征
并发症
预后
early onset preeclampsia
nephrotic syndrome
complication
prognosis
