摘要
重症急性胰腺炎(SAP)病人发生重度血容量缺乏后可采取"控制性液体复苏策略"积极处理。液体复苏策略包括缩短组织缺氧和防止液体潴留。前者包括恢复体液正常分布和尽早机械通气;后者包括控制液体输入、改善内皮细胞功能和缓解全身炎性反应综合征(SIRS)。恢复体液正常分布的措施包括三部分,首先是血容量扩充,一旦扩充达标即应转为第二步,体液分布调控,直至达到SIRS消失,也就是液体复苏终点。积极处理液体复苏引起的并发症可以显著改善预后。
Patients with severe volume deficient in SAP should be treated with controlled fluid resuscitation. Strategies of fluid resuscitation include shortening of histanoxia and prevention of fluid sequestration. The former includes restoration of normal distribution of body fluid and mechanical ventilation as early as possible; the latter includes controlled fluid infused, amelioration of endothelium function and relief of SIRS. Expansion of blood volume, regulation of body fluid distribution and disappearance of SIRS are the major three measures of restoration of normal distribution of body fluid. A positive response included the fulfillment of two or more of four criteria. Comphcations resulting from fluid resuscitaion treated actively may ameliorate prognosis.
出处
《中国实用外科杂志》
CSCD
北大核心
2012年第7期545-548,共4页
Chinese Journal of Practical Surgery
关键词
重症急性胰腺炎
液体复苏
severe acute pancreatitis
fluid resuscitation
