摘要
目的探讨新生儿胆红素脑病的致病因素以及临床治疗的效果。方法总结40例新生儿胆红素脑病的临床资料,对致病因素以及临床治疗的效果进行总结和分析。结果诱发新生儿胆红素脑病的主要因素为:感染性疾病47.5%(19/40)和溶血性疾病32.5%(13/40);观察组对患儿进行换血治疗、给予蓝光照射、丙种球蛋白等综合治疗后,与对照组给予常规治疗的38例患儿进行比较,治疗后的NBNA评分改善情况,差异具统计学意义(P<0.05)。结论感染和溶血性疾病是导致新生儿胆红素脑病的最危险因素,换血等综合治疗可有效改善患儿的NBNA评分,是临床有效的治疗方法。
Objective To discuss the pathogenic factors and clinical treatment effects of neonatal bilirubin encephalopathy.Methods The clinical data of 40 newborns with bilirubin encephalopathy were selected and analyzed.40 newborns were divided into the observation group and the control group.The pathogenic factors and clinical treatment effects were summarized.Results The major pathogenic factors of neonatal bilirubin encephalopathy were infectious diseases（47.5%,19/40） and hemolytic diseases（32.5%,13/40）.Newborns in the observation group received blood exchange transfusion,blue ray irradiation and gamma globulin,while the control group received conventional treatment.The NBNA value in observation group improved significantly,and the improvement in observation group were more significant than control group（P 0.05）.Conclusions Infectious and hemolytic diseases are the major pathogenic factors of neonatal bilirubin encephalopathy.The comprehensive treatments including blood exchange transfusion,blue ray irradiation and gamma globulin can improve the NBNA value,which is an effective method.
出处
《临床医学工程》
2012年第7期1110-1111,共2页
Clinical Medicine & Engineering
关键词
胆红素脑病
致病因素
临床疗效
Neonatal bilirubin encephalopathy
Pathogenic factor
Clinical effect
