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地佐辛与曲马多抑制瑞芬太尼致痛觉过敏作用的效果比较 被引量:2

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摘要 目的比较地佐辛与曲马多抑制瑞芬太尼致痛觉过敏的效果。方法选择接受瑞芬太尼麻醉的手术患者128例,随机分为观察组和对照组各64例。手术完成前30min,观察组给予曲马多2.0mg/kg静脉注射,对照组给予地佐辛0.1mg/kg静脉注射。观察2组患者自主呼吸恢复时间、苏醒时间、拔管时间、视觉模拟评分(VAS)和不良反应。结果 2组患者自主呼吸恢复时间、苏醒时间、拔管时间比较差异均无统计学意义(P>0.05)。观察组VAS评分、不良反应发生率均低于对照组,差异均有统计学意义(P<0.05)。结论采用曲马多抑制瑞芬太尼致痛觉过敏,可取得较满意的效果,值得临床推广应用。
作者 应启益
出处 《临床合理用药杂志》 2012年第22期96-96,共1页 Chinese Journal of Clinical Rational Drug Use
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