摘要
目的:探讨冠状动脉搭桥手术患者术后应激性血糖与术前糖化血红蛋(HbA1c)的关系。方法:回顾分析96例无糖尿病史且行心脏冠状动脉搭桥手术患者,术前完善了口服葡萄糖耐量(OGTT)试验除外糖尿病,根据HbA1c值分为相对高糖化组(HbA1c≥6.0%)和对照组(HbA1c<6.0%),观察2组术前基线指标和术后应激性血糖有无差异及相关性。结果:高糖化组与对照组术前年龄(P=0.001)、体质量指数(BMI)(P=0.007)、腰臀比(WHR)(P=0.0001)、胰岛素抵抗(HOMA-IR)指数(P=0.001)以及术后应激性血糖(P=0.0001)差异均有统计学意义;高糖化组术后应激性高血糖患者明显多于对照组(P=0.001),线性回归分析显示术前HbA1c值和应激性血糖密切相关(R2=0.224)。结论:术前超质量或腹型肥胖尤其是年龄大者,即使无糖尿病也应测定HbA1c,如果HbA1c≥6.0%应积极防治术后应激性高血糖。
Objective：To investigate the relationship of stress-blood glucose and HbAlc in patients af- ter coronary artery bypass, nethods：Ninty six patients with no diabetic history took standardized oral glucose tolerance test before surgical coronary artery bypass to rule out diabetes the basic blood glucose and stress-blood glucose, values were compared between HbA1 c ≥ 6. 0% group and HbAlc 〈 6.0% group. Results： Age （ P = 0.001 ）, Body Mass Index （ P = 0. 007 ）, Waist-hip ratio （ P = 0. 000 ）, Insulin-resistance index （HOME-IR） （P = 0. 001 ） and Stress-blood glucose （P = 0. 000） values in the group（ HbA1 c ≥6.0% ） were all significantly higher than the control group（HbAlc 〈 6. 0% ）. HbAlc were significantly correlated to stress-blood glucose. （R2 = 0. 224）. Conclusion： HbA1 c should be measured in the older patients with abdominal obesity before sur- gery in spite of no diabetes. If HbAlc was greater than or equal to 6. 0%, prevention and treatment of stress- hyperglycemia should be taken.
出处
《心肺血管病杂志》
CAS
2012年第4期428-429,共2页
Journal of Cardiovascular and Pulmonary Diseases
关键词
应激性血糖
冠状动脉搭桥术
胰岛素抵抗
腹型肥胖
Stress-glucose
Coronary artery bypass graft
Abdominal obesity
Insulin resistance
