2Yancopoulos GD,Davis S,Gale NW,et al.Vascular specific growth factors and blood vessel formation[J].Nature,2000,407(6801):242-248.
3Hanahan D,Folkman J.Patterns and emerging mechanisms of the angiogenic switch during tumorigensis[J].Cell,1996,86:353~364.
4Cresset R,Wattananupong O,Lertprasertsuke N,et al.Alteration of protein expression pattern of vascular endothelial growth factor (VEGF) from soluble to cell-associated isoform during tumourigenesis[J].BMC Cancer,2005,5(1):128-134.
6Arispe MLL,Dvorak HF.Angiogenesis:a dynamic balance of stimulators and inhibitors[J].Thromb Haemo,1997,78:672-677.
7Boocock CA,Charnock Jones DS,Sharkey AM,et al.Expression of VEGF and its receptors flt and KDR in ovarian carcinoma[J].J Natl Cancer Inst,1995,87(7):506-516.
8Asai T,Ueda T,Itoh K.Establishment and characterization of a murine osteosarcoma cell line(LM8)with hish metastatic potential to the lung[J].Int J Cancer,1998,76(3):418-422.
9Vineenti V,Cassano C,Rocchi M,et al.Assignment of the vascular endothelial growth factor gene to human chromosome 6p21.3[J].Circulation,1996,93[J]:1493-1495.
10Barleon B,Totzke F,Herzog C,et al.Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1[J].Biol Chem,1997,272(16):10382-10388.