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坦索罗辛和呋塞米联合治疗输尿管下段结石的临床研究 被引量:3

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摘要 目的:研究α1-肾上腺素能受体阻滞剂坦索罗辛和呋塞米治疗输尿管下段结石的疗效。方法:将90例输尿管下段结石患者采用随机分为组1、组2和组3各30例。3组均口服喹诺酮类抗生素,组1加服呋塞米,组2加服坦索罗辛,组3同时加服呋塞米和坦索罗辛。呋塞米20 mg,3次/日,坦索罗辛0.4 mg,1次/日,共服两周。比较各组疗效。结果:90例总排石率80%(72/90)。组1有21例(70%)排出结石,组2有23例(77%)排出结石,组3有28例(93%)排出结石,组1和组2比较差异无统计学意义,组1、组2与组3比较差异具统计学意义(P均<0.05)。组1排石时间为(10.3±0.3)d,组2为(10.5±0.4)d,组3为(5.0±0.2)d,组1和组2比较差异无统计学意义,组1、组2与组3比较差异具统计学意义(P均<0.05)。组1有5例(17%)发生肾绞痛,组2有6例(20%),组3有1例(3%),组1和组2比较差异无统计学意义,组1、组2与组3比较差异具统计学意义(P均<0.05)。结论:坦索罗辛和呋塞米合用疗效较好,且安全。
作者 曾祥建
出处 《新医学》 2012年第7期497-498,共2页 Journal of New Medicine
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