摘要
目的 明确社区范围高血压综合防治的效果。方法 利用Meta analysis对 1970～ 1997年各国符合条件的高血压综合防治试验进行了综合评价 ,12个试验进入了本次研究。根据对研究间异质性检验结果 ,采用相应的模型 :固定效应模型或随机效应模型。结果 高血压社区综合干预措施可在人群水平引起收缩压平均下降 1.75mmHg(s x0 .5 7mmHg) ,舒张压平均下降1.45mmHg(s x0 .43mmHg) ,在总人群及女性人群引起体重指数 (BMI)平均下降 0 .2 4kg/m2 (s x0 .0 8kg/m2 )和 0 .32kg/m2 (s x0 .15kg/m2 ) ,可使 2 5 .0 7%和 40 .45 %的高血压患者得到治疗和控制 ,减少高血压患病率2 .97% ,在中国人群可引起脑卒中发病率下降 133/ 10万 ,对人群水平的吸烟率及高血压患者知晓率未有明显影响。结论 表明社区范围的高血压人群综合干预措施对减少人群高血压的危险因素水平、增加高血压患者的治疗率和控制率、减少高血压患病率和减少脑卒中患病率均有效果。
Objective To evaluate the effectiveness of multiple risk factor interventions for hypertension prevention in the community. Method Twelve trials of multiple risk factor interventions for communitywide hypertension prevention according to the selective criteria were assessed by Meta analysis, from 1970 to 1997. According to the heterogeneity of the studies, two different models,namely, Fixed Effect Model and Random Effect Model, were applied to analyze the results. Results The intervention effects of community based hypertension control trials were estimated to be: a 1.75 mmHg( s 0.57 mmHg) net decrease in mean systolic blood pressure, a 1.45 mmHg ( s 0.43 mmHg) net decrease in mean diastolic blood pressure in general population, 0.24 kg/m 2 ( s 0.08 kg/m 2) and 0.32 kg/m 2 ( s 0.15 kg/m 2) net decreases in body mass index among the total population and female population respectively, a 2.97 % reduction in hypertension prevalence, and a 133/ 100 000 reduction in stroke prevanlence in the Chinese population. The intervention effects for the treatment and controlled of hypertensive were significant to increase 25.07 % and 40.45 % in the rates and controlled of treatment respectively. No significant changes were noticed in the rates of smoking and hypertensive awareness in the general population. Conclusion The results showed that the community based multiple risk factor interventions for hypertension had positive impaction the reduction of risk factors to hypertension,thus to incease the effects on treatment and control of hypertension, decrease prevanlences of hypertension and stroke.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2000年第3期171-176,共6页
Chinese Journal of Epidemiology
关键词
高血压
综合防治
META分析
社区控制
Hypertension
Multiple risk factor interventions
Community based
Meta analysis
