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血清脂联素、瘦素在糖尿病性视网膜病变早期诊断中的应用 被引量:4

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摘要 目的:探讨血清脂联素和瘦素与糖尿病性视网膜病变(Diabetic Retinopathy,DR)发展的关系。方法:对116例DR患者行眼底荧光素造影术,并将其分为两组:PDR组为增生性糖尿病性视网膜病变(Proliferative Diabetic Retinopathy,PDR)组,共61例;NPDR组为非增生性糖尿病性视网膜病变(Nonproliferative Diabetic Retinopathy,NPDR)组,共55例。同时选取60例健康者为对照组NC,分别检测各组人群的血清脂联素和瘦素水平,分析血清脂联素和瘦素与DR的关系。结果:与NPDR组比较,PDR组的血清脂联素和瘦素水平差异有统计学意义(P<0.05);与NC组比较,PDR、NPDR两组血清脂联素和瘦素水平差异有统计学意义(P<0.05)。结论:血清脂联素含量与DR病变严重程度成显著负相关,血清瘦素则与其呈显著正相关,二者联合应用,对DR的早期诊断有着重要的意义。
出处 《求医问药(下半月刊)》 2012年第6期107-107,共1页 Seek Medical and Ask The Medicine
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