摘要
目的:分析《中医方剂大辞典》收录治疗遗精方剂的处方用药及配伍规律,为临床治疗遗精提供参考。方法:筛选《中医方剂大辞典》收录治疗遗精的方剂,基于中医传承辅助软件系统,采用软件集成的改进互信息法、复杂系统熵聚类等数据挖掘方法对筛选方剂进行处方分析。结果:共筛选370首治疗遗精方剂,涉及中药282味。方中补益、固涩、安神之品出现频数较高。方中出现频数最高的单味药为茯苓(129次),占总处方数的34.9%;方中出现频率最高的药对为山药-茯苓(66次),3味中药组合为山药、五味子、熟地黄(35次),4味中药组合为山茱萸、山药、熟地黄与茯苓(22次)。关联分析结果显示,在治疗遗精的方剂中知母常配黄柏,莲须常配芡实;山茱萸、茯苓常配山药,巴戟天、茯苓常配肉苁蓉。演化得到核心组合36个,新处方7首。结论:《中医方剂大辞典》收录治疗遗精方剂组方以补益中药为主,辅以安神、固涩之品,标本兼治,可为中医药临床治疗遗精提供一定参考。
Objective： To analyze the composing principles of the prescriptions for seminal emission collected in （The Dictionary of Prescriptions in Traditional Chinese Medicine） using TCM inheritance system. Method： The prescriptions treating seminal emission in the （Dictionary of Prescriptions in Traditional Chinese Medicine） were collected and the composing principles were analized by using revised mutual information, complex system entropy clustering and so on based on the TCM inheritance system. Result： Three hundred and seventy prescriptions involving 282 herbs were studied. The herbs for invigoration or astringent were used in the highest frequency, of which, Poria appeared 129 times, being 34.9% in total prescriptions. Rhizoma Dioscoreae and Poria as a pair of herbs appeared 66 times, Rhizoma Dioscoreae, Fruetus Schisandrae Chinensis and Radix Rehmanniae Praeparata as a 3 item set appeared 35 times, Fructus Corni, Rhizoma Dioscoreae, Pradix Rehmanniae Praeparata and Poria as a 4 item set appeared 22 times, being the highest in frequency. The analysis on association rule showed that Rhizoma Anemarrhenae was coupled with Cortex Phellodendri Chinensis, Stamen Nelumbinis with Semen Euryales, Fructus Corni and Poria with Rhizoma Dioscoreae, Radix Morindae Officinalis and Poria with Herba Cistanches. Thirty six core combinations and seven new prescriptions are mined from the database. Conclusion： The prescriptions for treating seminal emission are mainly composed with herbs for invigoration,assisted by tranquilizing and/or astringent herbs. This pattern will provide a reference for clinical practice.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第16期1-4,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家重大新药创制专项(2009ZX09301-005)
关键词
中医方剂大辞典
遗精
配伍规律
中医传承辅助系统
数据挖掘
the dictionary of Prescriptions in Traditional Chinese Medicine
seminal emission
composition principle
TCM inheritance system
data mining
