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国内部分地区三级综合医院外科大量输血输注新鲜冰冻血浆与红细胞比例及其死亡率分析 被引量:32

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摘要 目的了解国内大量输血中新鲜冰冻血浆(FFP)与红细胞悬液(RBC)应用比例的现状,探讨大量输血时输注FFP与RBC的适宜比例。方法采用统一的《调研表》及调查项目指标,在统一的时间内分别收集全国不同地区20家三级综合医院大量输血病历(例)的数据资料,并在统一回收《调研表》后作数据处理和多中心回顾性分析。结果用于处理和分析的大量输血合格病例占全部回收《调研表》的91.33(1 601/1 753),从中显示:大量输血患者≤24 h输注FFP∶RBC=1∶(1~2)时,死亡率最低[9.31%(55/591)],而FFP∶RBC>2∶1或<1∶(2.5~4)时,死亡率分别上升至11.44%(31/271)和11.83%(22/186)(P>0.05);≤72 h输注FFP∶RBC=1∶(1~2)时,死亡率最低[7.25%(34/469)],而FFP∶RBC>2∶1或<1∶(2.5~4)时,死亡率分别上升至13.65%(58/425)和10.39%(16/154)(P<0.01)。结论大量输血时,≤24 h或≤72 h的RBC输注量与患者的死亡率有一定的关联;大量输血患者≤72 h输注FFP∶RBC的适宜比例为1∶(1~2),而比例过高或过低均是增加患者死亡率的因素。
出处 《中国输血杂志》 CAS CSCD 北大核心 2012年第7期628-631,共4页 Chinese Journal of Blood Transfusion
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参考文献24

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