摘要
目的:探讨莫西沙星所致不良反应的类型及其特点,为临床安全用药提供参考。方法:在中国科技期刊数据库(维普资讯)和中国期刊全文数据库(中国知网)中,以"莫西沙星"和"不良反应"为关键词,搜索2005年～2011年11月莫西沙星所致不良反应文献,并进行统计分析。结果:收集到62例莫西沙星导致的不良反应,主要类型有神经系统反应(28.4%)、过敏反应(21.6%)、心血管系统反应(14.9%)、消化系统反应(10.8%)、呼吸系统反应(6.8%)等。70岁以上的患者占46.8%(29/62),高于其他年龄段。静脉滴注给药者占59.7%(37/62)。结论:临床应高度重视莫西沙星的不良反应,加强用药监护。
Objective： To explore the type and characteristics of adverse drug reactions （ADRs） induced by moxifloxacin to provide reference for the clinical rational use of drugs. Methods ： Based on the VIP and CNKI database, litera- tures about moxifloxacin-induceA ADRs from 2005 to 2011 were collected and statistically analyzed. Results：In 62 case of patients, main clinical manifestations of moxifloxacin-induced ADRs were nervous system reactions（28.4% ）, allergic reac- tions （21.6%）, cardiovascular system reactions（ 14.9% ）, digestive system reactions（ 10.8% ）, respiratory system reactions （6.8%）, etc. The patients aged more than 70 were 29 cases, accounting for 46.8%. Intravenous drips were 37 cases, ac- counting for 59.7%. Conclusion：In clinical application, more attention should be paid to the moxifloxacin-induced ADRs, and the strict monitor of the drug use should be strenghtened.
出处
《药物流行病学杂志》
CAS
2012年第7期349-351,共3页
Chinese Journal of Pharmacoepidemiology
关键词
莫西沙星
药品不良反应
文献分析
Moxifloxacin
Adverse drug reactions
Literature analysis
