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党参多糖体内抗肿瘤活性研究及急性毒性实验 被引量:22

Study of Polysaccharides in Codonopsis Pilosula on Antineoplastic Activity in Vivo and the Acute Toxicity Testing
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摘要 目的:党参多糖体内抗肿瘤活性实验的初步研究。方法:对腹腔荷S180腹水瘤细胞小鼠灌胃党参多糖1 g/kg.d-1,连续7天后记录小鼠的生存天数。结果:与对照组相比,荷S180腹水瘤细胞小鼠的生命延长率为34.29%。结论:党参多糖可以延长腹腔荷S180腹水瘤细胞小鼠的存活时间。 Objective: To study initially the pharmacological effect of polysaccharides in codonopsis pilosula on antitumor in vivo. Methods: The models of mice bearing S180 ascites tumor cells in abdominal cavity were given to polysaccharides in codonopsis pilosula by gavage as the dosage of 1 g/kg·d. After 7 days their survival time was measured and recorded. Results: The survival time was prolonged in treatment group compared to control group, and the rate was 34.29%. Conclusion: Polysaccharides in codonopsis pilosula can prolong the survival time of mice bearing S180 ascites tumor cells in abdominal cavity.
出处 《山西中医》 2012年第8期49-50,共2页 Shanxi Journal of Traditional Chinese Medicine
基金 科技部国家科技支撑计划项目(编号:2011BAI07B07)
关键词 党参多糖 体内抗肿瘤 急性毒性实验 实验研究 polysaccharides in codonopsis pilosula, antitumor in vivo, acute toxicity testing, experimental study
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